Experience with onabotulinumtoxinA (BOTOX) in chronic refractory migraine: focus on severe attacks

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OnabotulinumtoxinA (Botox) in chronic migraine with and without medication overuse

Chronic Migraine (CM) is one of the most disabling primary headache disorders affecting 2% of general population. CM is defined as headaches on >15 days per month for >3 months of which >8 days fulfill the criteria for migraine with or without aura or relieved by migrainespecific treatment [1].CM has an important economic and social impact compared with episodic migraine [2]. CM patients requir...

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OnabotulinumtoxinA for the treatment of chronic migraine.

Chronic migraine is a common primary headache disorder that actively afflicts as many as 1 in 50 individuals and accounts for a disproportionate share of the financial cost, pain, and emotional suffering produced by migraine generally. “Chronic migraine” implies that one has an established history of migraine, has been experiencing headaches on at least 15 days of each month for at least 3 cons...

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Prolonged Effect of OnabotulinumtoxinA on Chronic Migraine in 87 Koreans

Dear Editor, OnabotulinumtoxinA (BOTOX) has been approved for prophylaxis in chronic migraine (CM) since 20101 based on the findings of the Phase 3 REsearch Evaluating Migraine Prophylaxis Therapy (PREEMPT) trial.2 The duration of BOTOX efficacy is known to be 3 months, but prolonged efficacy (>3 months) after a single cycle of BOTOX has not been evaluated thoroughly. Moreover, the efficacy and...

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ژورنال

عنوان ژورنال: The Journal of Headache and Pain

سال: 2011

ISSN: 1129-2369,1129-2377

DOI: 10.1007/s10194-011-0294-8